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Table2-1. Hematologic, hematopoietic, and lymphatic systems

Structure and functionBone marrow structure
Structure and functionDifferentiation and maturation of hematopoietic stem cells
Structure and functionMajor hematopoietic growth factors (erythropoietin, granulocyte colony-stimulating factor (G-CSF), thrombopoietin)
Structure and functionStructure and function of spleen, thymus, lymph nodes, tonsils, and Peyer’s patches
Structure and functionTypes and functions of plasma proteins
Structure and functionStructure and function of red blood cells and hemoglobin
Structure and functionTypes and functions of white blood cells
Structure and functionFunctions of platelets and mechanisms of hemostasis, coagulation, and fibrinolysis
SymptomsGeneral malaise
SymptomsCoagulation defect
Methods of examinationPeripheral blood smear
Methods of examinationFunction studies of coagulation, fibrinolysis, and platelets
Methods of examinationBone marrow examination (bone marrow aspiration, bone marrow biopsy)
Methods of examinationTransfusion related lab tests
Methods of examinationProtein fractionation and immunoelectrophoresis
Methods of examinationGenetic testing and chromosome analysis
Specific therapiesBlood transfusion
Specific therapiesHematopoietic stem cell transplantation